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WARNING: This product contains nicotine. Nicotine is an addictive chemical.
Nicotine salts. It’s the new thing on the block and smokers and vapers alike are flocking to it to quit cigarettes for good.
If you haven't heard of it before, nicotine salt basically allows you to vape at higher nicotine strengths without getting the rough throat hit you’re typically used to. This also means you get more bang for your buck! You end up vaping less because you get a lot more nicotine. So, if you love that light headed feeling, but hate having to vape 24/7, nic salts may be right for you.
As you may already know, the higher nicotine level you go, the throat hit becomes harsher. It can turn off a lot of smokers transitioning into vaping if they have to endure the harsh throat hit while also not getting the level of buzz that you would otherwise get in a cigarette. Not to mention, it can be a hassle for new vapers to figure out how to get a simple nicotine fix with the advancements in vaping technology in the past several years.
For those who are interested in learning more about salt nicotine and what it can do for you, you’re in the right place. So, what’s the difference between salt nicotine and what people are vaping now?
The nicotine in your vape juice that you are familiar with is something called freebase nicotine. It is a method that tobacco companies have been using since the 60’s.
Freebase means that the nicotine is in its purest form compared to the other nicotine derivatives. In turn, the nicotine is much more potent when heated and it can be absorbed much faster in your lungs and in your brain.
This method was found in the 1960’s by Phillip Morris, the company that owns Marlboro. What they found is that if they manipulate the pH levels in nicotine, it can provide more of a kick than the previous cigarettes in the 1950’s without increasing the dose, making Marlboro cigarettes more addictive. This was a major breakthrough for Marlboro and they enjoyed this competitive advantage for years as they became one of the most popular brands or addicting cigarettes in the world.
In order to understand what nicotine salt is, it’s important to understand how freebase nicotine works. About to get science-y here so bear with me.
Nicotine in tobacco leaves has the chemical composition of a salt. A salt is made up of a chemical reaction that has a positive charge (Acid) and negative charge (Base).
Nicotine’s chemical nature is a weak base and made up of negatively charged particles. As a base, it seeks to find positively charged particles (Protons) to find stability and become Ionized. Nicotine in tobacco leaves or ions is not the most effective way of delivering nicotine into our bodies because ions have a harder time moving across organic membranes and are not easily vaporized.
This is where freebasing comes in. Phillip Morris found that if the nicotine was de-protonated (via ammonia) or to remove its positive charge, it can go back to its free state where it will be much easier to travel across membranes in our bodies. In a nutshell, nicotine in its freebase form makes it more bioavailable to your lungs and to your brain which makes it more potent.
Phillip Morris found that impregnating tobacco with a salt like diammonium phosphate releases ammonium when the cigarette is combusted thereby freeing the nicotine into free base form.
If freebase nicotine is more potent, then why are smokers gravitating to nicotine salts?
Nicotine salt as we explained above is the natural state that nicotine is in tobacco leaves.
We also mentioned that nicotine salt is much more stable and not as volatile as the freebase form. Salt nics also take higher temperatures to vaporize and the ions don’t easily travel to your nicotine receptors in your body.
To put simply, it’s not the most effective way to deliver nicotine to your body compared to the de-protonated freebase form.
So, what’s all the craze about?
Pax labs, the innovator of this new vaping method found a way to use nicotine salt as a means to make 50 mg nicotine palatable while making it more bioavailable than what we have currently in the vaping market. Their goal was to mimic the sensation of smoking a cigarette as closely as possible and so far, it looks like it’s working.
How is this possible? Many of you are probably a little confuddled right now. The secret ingredient that makes all of the magic happen lies in the use of benzoic acid. Benzoic acid serves two key purposes in salt nicotine:
What this means is that you can vape comfortably at high nicotine levels such as 50 mg and it also makes it easier for your body to absorb nicotine contrary to the nature of nic salts. It seems from Pax’s patent that it only works on specific salt nicotine formulation with certain types of acids. As you can see in the graph provided by PAX labs, the nicotine salt e-liquid can help you deal with your cravings more effectively than regular vape juices.
If you look at the purple and green line above, the amount of nicotine absorbed into the bloodstream is comparable to smoking a cigarette and can provide greater nicotine satisfaction than traditional e-liquids in the market.
From a vaping perspective, the difference between freebase nicotine and nicotine salt is a matter of how it affects your vaping experience.
One noticeable difference is the harshness induced by higher nicotine levels. Freebase nicotine has a higher pH level which affects the alkalinity. What this does is that it makes freebase e-liquid taste harsher as you climb the nicotine ladder. Whereas, salt nicotine have a lower alkalinity due to the benzoic acid which gives you a reportedly smoother throat hit and makes vaping at 50 mg nicotine bearable.
The second difference is how the two travel through your body. Even though nicotine salts are known to be not the most effective way to deliver nicotine, Pax Labs have supposedly figured out a way to make it more effective than freebase nicotine. This is due to the benzoic acid added to the salt nicotine as the nicotine becomes much more readily available and more effective than traditional freebased e-liquids.
One thing to keep in mind is that salt nics operate in lower wattage devices. It is strongly recommended to avoid using high powered devices to vape salt nicotine. Using sub-ohms to vape salt nicotine at 50 mg nic levels will give you excessive amounts of nicotine and would be fairly unpleasant.
As we have stated above, the salt nics are designed to be used in lower wattage devices due to the higher amount of nicotine absorbed as well as not requiring to vaporize at higher temperatures.
Not only are the devices low profile and sleek, most of the low wattage devices are autofire meaning you only get vapor when you inhale it. This makes it a user-friendly device for any smokers who are new to vaping without the investment in figuring how all of the current devices work.
The low wattage, high resistance devices that are currently on the market come with two available options:
Side note: You can also consider getting lower nicotine levels like 3 mg and 6 mg in nicotine salt form for your sub-ohm device. As far as it being more effective at delivering nicotine than freebase nicotine as PAX lab claims in their study is up to debate. What you may notice is a smoother throat hit than freebase nicotine e-juices.
Great question! One of the main ingredients in nic salts, nicotine, is highly addictive. And nic salts have a higher amount of nicotine than freebase vape. Making the possibility for increased nicotine addiction a possibility if proper precaution is not taken.
Another ingredient in nic salt, benzoic acid, is still under review to determine its toxicity. Studies have reported that once benzoic acid is inhaled has caused coughing. Some people are also allergic to this ingredient which has also caused concern.
Let us know in the comments if you have any questions or would like to share your experiences with nicotine salt. And feel free to browse our mouthwatering nicotine salt e-juice collection!
If you found this article helpful, read our beginner's guide to nicotine salt to see if nic salts are a good fit for you!
March 21, 2018
I’m a bit confused. Would a Druga RDA be something that you would NOT use the salt based juices with?
March 17, 2018
My organic chem may be a bit rusty but I think your 2 nicotine structures are both the same. The line coming off the pyrrolidine nitrogen (upper left) represents a methyl group, ie CH3 (upper right), in geek chemist pictograms. The salt formation comes about by an acidic hydrogen forming a “hydrogen bond” to the lone pair of 2p-electrons (not shown) on the nitrogen atom. The acid hydrogen forms a sort-of bridge linkage between the nicotine molecule and the rest of the acid molecule. The same thing can also happen at the pyridine nitrogen at low pH conditions. But I won’t get into the equilibria here because the rust is too too much.
March 02, 2018
Hey Lesley! Awesome stuff!! The first two weeks are the hardest to quit smoking and big ups on making over that hump! Experts recommend 50 mg as a starting point for heavy smokers and Juuls are a great way to get started. If you’re interested in similar devices, check out the Phix.
Vaping doesn’t always have to be about the nicotine and you can always make it a richer experience by entering into a whole new world of flavors :) If you’re interested, try out some of the open pod systems out there. You’ll get a slightly airier draw and a wider range of flavor selection. Psss, they will save you money in the long run. Happy for you Lesley and Keep it up!
March 01, 2018
On day 10 no cigs I bought a JUUL and this is the first time I’ve been totally satisfied using a vap. I haven’t looked back nor craved a cigarette at all. I am using 5 mg pods and the hits are so smooth yet a very satisfying throat hit. Yeah!!
February 16, 2018
Hello Jon! That’s awesome to hear you’re staying away from the stinkies !! and for sure dude, using nic salts as a secondary device is super handy when you’re out with friends and such. If you haven’t tried open pod systems, it’s a great way to try out a variety of flavors in nicotine salt form. Plus they have an airer draw than closed pod systems like Juuls or Phix. Here is an article about vape pods if you’re interested: https://www.ruthlessvapor.com/blogs/ruthless-e-liquid/nicotine-salt-devices-vape-pods Happy vaping and always glad to hear a fellow vaper staying away from smoking!
February 15, 2018
I just purchased a juul and its the first time a vape has succesfully kept me from smoking. I also smoke it much less a week after buying it, yet still thoroughly enjoy it. Im seriously impressed with paxs work.
Ill still probably vape freebase juice, but more for fun than my nic fix
January 29, 2018
The compound itself is called a salt due to its ionized state. To answer your question, it’s not the same thing as table salt. However, chemically speaking, the compounds are similar.
As far as being swollen, it is most likely due to being dehydrated. Vaping nicotine salt or freebase nicotine will cause dehydration since both e-juices contain PG. If you aren’t familiar witht he ingredients in your vape juice, there are 4 main ingredients: PG, VG, Flavoring, and Nicotine. PG is a humectant and it will retain water which will take moisture away from your saliva and may cause a sore throat.
A good practice for new vapers is to drink more water than you usually do. Chain vaping will further amplify this effect so be wary of any symptoms of dehydration. If the PG ratio is high in your e-juice, I would recommend playing around with a lower PG e-juice and see if that will do the trick. Let me know if this helps!
Brian from Ruthless!!
January 25, 2018
When we talk about nicotine salts in that compound is there any similarity to actual salt?
The reason I ask, is since I have using the juul I find my body retaining water, swollen.
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Brian From Ruthless
March 21, 2018
Hey Tony, thanks for reading and much appreciated on the correction! We are in the process of uploading a new diagram!!
H.S. James, Yes you are correct. Nicotine salts with high nicotine strengths such as 25 – 50 mg are not recommended in high wattage or sub-ohm devices. However, there are DIYers who make 3 and 6 mg juices using a nicotine salt formulation for an ultra-ultra smooth throat hit! Let me know if that helps or if you have any other questions :)